
Inflammatory Bowel Disease (IBD)
Known Symptoms
- Common symptoms:
- Diarrhoea (often bloody in UC, watery in CD).
Abdominal pain/cramping (more focal in CD, left-sided in UC). - Urgency, tenesmus (especially in UC).
- Weight loss, fatigue, and fever.
- Diarrhoea (often bloody in UC, watery in CD).
- Extra-intestinal manifestations:
- Joints (arthralgia/arthritis), skin (erythema nodosum, pyoderma gangrenosum), eyes (uveitis, episcleritis).
- Red-flag symptoms:
- Severe abdominal pain, persistent vomiting (suggesting obstruction or toxic megacolon).
- Profuse bleeding, unexplained weight loss, and signs of sepsis.
Known Causes
- Local:
- Strictures, fistulae, abscesses (CD).
- Toxic megacolon, perforation (UC).
- Malnutrition, growth failure (in pediatric IBD).
- Increased risk of colorectal cancer (long-standing UC/extensive CD).
- Bone loss (osteoporosis/osteopenia).
Care
- Prevention: No known prevention; smoking cessation reduces CD risk/flares.
- Follow-up:
- Regular monitoring of disease activity (symptoms, biomarkers, endoscopy).
- Vaccinations (avoid live vaccines on immunosuppressants).
- Bone density screening, dermatologic/ophthalmic exams for extra-intestinal manifestations.
- Colonoscopic surveillance for dysplasia in long-standing colitis.
- Common symptoms:
- Diarrhoea (often bloody in UC, watery in CD).
Abdominal pain/cramping (more focal in CD, left-sided in UC). - Urgency, tenesmus (especially in UC).
- Weight loss, fatigue, and fever.
- Diarrhoea (often bloody in UC, watery in CD).
- Extra-intestinal manifestations:
- Joints (arthralgia/arthritis), skin (erythema nodosum, pyoderma gangrenosum), eyes (uveitis, episcleritis).
- Red-flag symptoms:
- Severe abdominal pain, persistent vomiting (suggesting obstruction or toxic megacolon).
- Profuse bleeding, unexplained weight loss, and signs of sepsis.
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